Collaborators
Sen Xu, Assistant Professor, Department of Biology
University of Texas at Arlington
Sen studies the patterns of mutation and recombination in eukaryotic genomes, the genetic mechanisms for the origin of obligately asexual reproduction, and organismal responses to environmental stress in freshwater ecosystems.
Lab webpage
University of Texas at Arlington
Sen studies the patterns of mutation and recombination in eukaryotic genomes, the genetic mechanisms for the origin of obligately asexual reproduction, and organismal responses to environmental stress in freshwater ecosystems.
Lab webpage
Weilong Hao, Assistant Professor,
Department of Biological Sciences, Wayne State University,
Weilong's primary research interest is to develop a better understanding of the highly dynamic genomic changes and their corresponding functional consequences. To accomplish this research, we conduct comparative genomic studies using next-generation sequencing, experimental and bioinformatics approaches. Much of our published work has been carried out on bacterial pathogens and eukaryotic mitochondria, and has focused on the exchange of genetic material between more or less distantly related genomes.
Lab webpage
Department of Biological Sciences, Wayne State University,
Weilong's primary research interest is to develop a better understanding of the highly dynamic genomic changes and their corresponding functional consequences. To accomplish this research, we conduct comparative genomic studies using next-generation sequencing, experimental and bioinformatics approaches. Much of our published work has been carried out on bacterial pathogens and eukaryotic mitochondria, and has focused on the exchange of genetic material between more or less distantly related genomes.
Lab webpage
Students at Indiana University
Chloe Strauss (December 2014-August 2017). Chloe started at IU in the fall of 2012 and has graduated from IU Biology in May 2017. She is a biology and anthropology major with an interest in coral reef and conservation biology. She will also receive a certificate in underwater resource management through the academic diving program and is a PADI certified divemaster. She is a coauthor of the Long et al. PNAS 2016 paper for her work on cell line transfers, DNA extractions and antibitoic resistance assays. She is also working on an honor thesis project on mutational responses to pH change in the coral reef pathogen Vibrio shiloi. She hopes to attend a graduate program where she is able to combine her love of diving with her molecular biology skills (Illumina genome library consturction, PCR, Sanger sequencing reactions, DNA extraction) to help research coral disease.
Ronald Te (February 2015-June 2016). Ron transferred to IU in Fall 2013 and graudated in Spring 2016 with a B.S. in biology and a minor in chemistry. His academic pursuits have earned him the John R. and Wendy L. Kindig Scholarship as well as induction into the Phi Beta Kappa honor society. After graduation, He hopes to attend medical school and obtain an M.D. He is a coauthor of the Long et al. PNAS 2016 paper, for his intensive work on antibitoic resistance assays, and another Long et al. paper on the red yeast Rhodosporidium toruloides (in preparation), for his work on PCR and Sanger sequencing. Ron is a medical staff in Chicago.
Katie Griffin (March 2015-August 2015). Katie started at IU in Fall 2011 and graduated May 2015 with a double major in Biology and Spanish. Currently, Katie works as a medical interpreter/medical assistant at the Volunteers in Medicine Clinic, a clinic providing free healthcare coverage to uninsured residents of Bloomington. In August, Katie is leaving the country to work as the Clinic Manager for Floating Doctors, an organization providing medical care to rural areas in Bocas del Toro, Panama. With the hopes of attending IU School of Medicine in Fall 2017, Katie is eager to begin her overseas clinical experience while expanding on her Spanish. Katie conducted intensive antibiotic resistance, survival assays on the antibiotic induced mutations project, and is a coauthor of the Long et al. 2016 PNAS paper. Katie is now a student of IU medical school.
Clayton Tincher (August 2015-March 2017). Clayton began attending IU in the fall of 2012 and has graduated in the spring of 2016. He is pursuing a B.S. in microbiology and a minor in biotechnology through the College of Arts and Science. In collaboration with Noah, he worked on a project to quantify potential mutagenic effects of the herbicide Roundup using mutation accumulation/whole-genome sequencing techniques. He is currently working on a project applying these techniques to measure baseline mutation rates in various strains of Salmonella enterica subsp. enterica and another porject on quantifying the contribution of the SOS response to antibiotic induced mutagenesis. He is experienced in bacterial cell line maintenance and streaking, DNA extraction and Illumina genome library construction. Clayton is working in Baxter International Inc.
Caitlyn Patterson (August 2015-August 2017). Caitlyn started at IU her sophomore year in 2014 and will be graduating in the Winter of 2017. She is a neuroscience and biology double major. She was involved in a project on mutational responses to pH change in the coral reef pathogen Vibrio shiloi, and is working on another porject on quantifying the contribution of the SOS response to antibiotic induced mutagenesis. She is also leading a mutation project using the bacterial pathogen Staphylococcus aureus.
Noah Walker (November 2015-August 2017). Noah is currently a senior in the College of Arts and Sciences at Indiana University in Bloomington Indiana. He started his college education at Ivy Technology Community College in the fall of 2011 and has finished his B.S. degree in Microbiology at IU in the spring of 2016. His career dream is to become a dentist and so he is applying to schools this summer. His extracurricular interests include soccer, running, gaming, hunting, fishing, ping pong, and the list goes on. Philosophically, He is dedicated to the teachings of Christ. He, in collaboration with Clayton, finished a project on quantifying potential mutagenic effects of the herbicide Roundup using mutation accumulation/whole-genome sequencing techniques. He is also working on a project, which would quantify the contribution of SOS response to antibiotic induced mutation elevation in Escherichia coli. He is very well trained in bacteria cell line maintaining/streaking, DNA extraction, Illumina genome library consturction.
Colin Gregory (February 2016-August 2017). Colin is a recent graduate of Indiana University, having graduated with a degree in Biology in 2015. Before transferring to IU, he attended Goshen College for two years, where he completed a minor in Music. Colin is new to the lab, and is currently working on a project studying the contribution of the SOS response to antibiotic-induced mutagenesis in E. coli. Colin is skilled in bacterial line maintenance, DNA extraction, DNA library construction, and many other molecular biology techniques. He hopes to attend medical school in 2017.
Iain Konigsberg (March 2016-August 2016). Iain has graduated in 2016 with a Bachelor's of Science in Biology with a minor in Informatics. He will attend University of Colorado at Denver's Anschutz Medical Campus as a part of the Human Medical Genetics & Genomics graduate program. He has been working in Lynch Lab since 2012, originally working under Dr. Way Sung (now assistant professor in University of Northern Carolina, Charlotte). He is studying mutation repair mechanisms as well as the effects of mutagens on mutation rate and spectra in bacteria. Iain is now a PhD student at Human Medical Genetics and Genomics Program at University of Colorado at Denver.
